Metabolic reprogramming is the hallmark of malignant tumors. Both metabolic phenotype and metabolic dependence are changed during the development of cancer from precancerous tissue to local invasion ...

Abstract: Recently, with the superior capacity for analyzing the multiplex graph data, self-supervised multiplex graph representation learning (SMGRL) has received much interest. However, existing ...

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in intrahepatic cholangiocarcinoma (ICC) remains unclear. Objective We ...

Test time has arrived: the first person has been treated in a highly anticipated gene-therapy trial that aims to coax aged cells to take on a younger identity. The clinical trial is testing an ...

The next step in the youth quest is a technology called chemical reprogramming. The outspoken longevity scientist David Sinclair has been predicting that one day, you’ll go to the doctor and get a ...

Abstract: The advent of smart terminals and the IOT era has prompted the emergence of the multiplex network system. With the rapid information transmission in multiplex networks, security incidents ...