Background Dipeptidyl peptidase-4 inhibitors (DPP-4is) have been reported to exhibit therapeutic effects in Parkinson’s disease (PD), increasing their potential for drug repurposing. One aspect of PD ...
Pakistan: Triple therapy combining metformin, SGLT-2 inhibitors, and DPP-4 inhibitors achieves superior glycemic control compared with dual therapy, improving blood glucose control without significant ...
Among patients with type 2 diabetes, the incidence of osteoarthritis and total knee or hip replacement was lower among DPP-4 inhibitor users vs nonusers. The use of dipeptidyl peptidase-4 (DPP-4) ...
The effects of the COVID-19 pandemic on cancer incidence and cancer-specific mortality. Hazard ratios (95% CI) for incident cancer, Marketscan databases, 2016-2022.
Abstract: Dipeptidyl peptidase 4 (DPP-4) are drug targets for type-2 diabetes mellitus (T2DM). The enzyme dipeptidyl peptidase 4 (DPP-4) can catalyze the decrease in the hormone incretin peptide, ...
Copyright: © 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Glucagon-like peptide-1 ...
Cancer Res (2026) 86 (7_Supplement): 1338. Exhaustion of CD8+ T cells in the tumor microenvironment is intertwined with metabolic dysfunction. Thus, metabolic reinvigoration of T cells is a promising ...
Compared with DPP-4 inhibitor therapy, sustained GLP-1 receptor agonist (GLP-1 RA) therapy was associated with greater short‑ and long‑term improvements in A1c levels and a modest reduction in the ...
In patients with type 2 diabetes (T2D), the risk of hospitalization for heart failure (HHF) was significantly lower with GLP-1RAs than DPP-4 inhibitors while it was similar compared with SGLT-2 ...
Novel treatments are needed for the primary and secondary prevention of heart failure in patients with type 2 diabetes, including individuals with and those without a history of heart failure.
China: A new multicenter phase 2 clinical trial, published in Diabetes, Obesity and Metabolism, suggests that cofrogliptin, administered once every two weeks, could offer an effective and ...
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